Gut Microbiome Alterations Associated with Diabetes in Mexican Americans in South Texas
Suet‐Ying Kwan, Caroline M. Sabotta, Aron Y. Joon, Peng Wei, Lauren E. Petty, Jennifer E. Below, Xiaogang Wu, Jianhua Zhang, Robert R. Jenq, Ernest T. Hawk, Joseph McCormick, Susan P. Fisher‐Hoch, Laura Beretta
Abstract
The gut microbiome composition varies across ethnicities and geographical locations, yet studies on diabetes-associated microbiome changes specific to high-risk Mexican Americans are lacking. Here, we aimed to identify specific alterations associated with diabetes in this population, as well as host genetic factors that may explain increased disease susceptibility in this ethnic group.
Topics & Concepts
Faecalibacterium prausnitziiMicrobiomePopulationMetagenomicsDiabetes mellitusType 2 diabetesBiologyGut floraProteobacteriaMedicineEnvironmental healthBioinformaticsImmunologyGeneticsEndocrinologyGene16S ribosomal RNABacteriaGut microbiota and healthClostridium difficile and Clostridium perfringens researchHelicobacter pylori-related gastroenterology studies