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A Prediction Model for High Risk of Positive RT-PCR Test Results in COVID-19 Patients Discharged From Wuhan Leishenshan Hospital, China

Yawei Qian, Guang Zeng, Yue Pan, Yang Liu, Limao Zhang, Kun Li

2021Frontiers in Public Health16 citationsDOIOpen Access PDF

Abstract

Several recent studies have reported that a few patients had positive SARS-CoV-2 RNA tests after hospital discharge. The high-risk factors associated with these patients remain to be identified. A total of 463 patients with COVID-19 discharged from Leishenshan Hospital in Wuhan, China, between February 8 and March 8, 2020 were initially enrolled, and 351 patients with at least 2 weeks of follow-up were finally included. Seventeen of the 351 discharged patients had positive tests for SARS-CoV-2 RNA. Based on clinical characteristics and mathematical modeling, patients with shorter hospital stays and less oxygen desaturation were at higher risk of SARS-CoV-2 RNA reoccurrence after discharge. Notably, traditional Chinese medicine treatment offered extensive benefits to reduce risk. Particular attention should be paid to those patients with high risk, and traditional Chinese medicine should be advocated.

Topics & Concepts

MedicineCoronavirus disease 2019 (COVID-19)Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)Emergency medicineTraditional Chinese medicine2019-20 coronavirus outbreakChinaInternal medicineIntensive care medicinePediatricsAlternative medicineVirologyDiseasePathologyInfectious disease (medical specialty)Political scienceLawOutbreakCOVID-19 Clinical Research StudiesSARS-CoV-2 and COVID-19 ResearchSARS-CoV-2 detection and testing