Substrate-selective positive allosteric modulation of PTPRD’s phosphatase by flavonols
Ian Henderson, Carlissa Marez, Karol Dokładny, Jane Smoake, María Jimena Martínez, David K. Johnson, George R. Uhl
Topics & Concepts
DephosphorylationPhosphataseAllosteric regulationProtein tyrosine phosphatasePhosphorylationCell biologyKinaseProtein phosphatase 2ChemistryBiologyBiochemistryCancer researchEnzymeProtein Tyrosine PhosphatasesGenomics, phytochemicals, and oxidative stressNatural product bioactivities and synthesis