Direct Delivery of Antisense Oligonucleotides to the Middle and Inner Ear Improves Hearing and Balance in Usher Mice
Jennifer J Lentz, Bifeng Pan, Abhilash Ponnath, Christopher M. Tran, Carl Nist-Lund, Alice Galvin, Hannah Goldberg, Katelyn N Robillard, Francine M. Jodelka, Hamilton E. Farris, Jun Huang, Tianwen Chen, Hong Zhu, Wu Zhou, Frank Rigo, Michelle L. Hastings, Gwenaëlle S. G. Géléoc
Topics & Concepts
Inner earMedicineVestibular systemUsher syndromeAudiologySensorineural hearing lossMiddle earHair cellHearing lossBalance (ability)Retinitis pigmentosaSurgeryOphthalmologyAnatomyPhysical medicine and rehabilitationRetinalHearing, Cochlea, Tinnitus, GeneticsRNA regulation and diseaseRNA and protein synthesis mechanisms