Discovery of novel 1,3,5-triazine derivatives as potent inhibitor of cervical cancer via dual inhibition of PI3K/mTOR
Junbo Hu, Yanli Zhang, Na Tang, Yanju Lu, Peng Guo, Ziming Huang
Topics & Concepts
HeLaPI3K/AKT/mTOR pathwayChemistryApoptosisCancer cellBlotCancerCell cycleCancer researchMolecular biologyCellBiochemistryBiologyInternal medicineMedicineGeneSynthesis and Characterization of Heterocyclic CompoundsSynthesis and biological activityQuinazolinone synthesis and applications