Litcius/Paper detail

Advances of Hydrogel Therapy in Periodontal Regeneration—A Materials Perspective Review

Maoxue Li, Jiaxi Lv, Yi Yan Yang, Guoping Cheng, Shujuan Guo, Chengcheng Liu, Yi Ding

2022Gels45 citationsDOIOpen Access PDF

Abstract

Hydrogel, a functional polymer material, has emerged as a promising technology for therapies for periodontal diseases. It has the potential to mimic the extracellular matrix and provide suitable attachment sites and growth environments for periodontal cells, with high biocompatibility, water retention, and slow release. In this paper, we have summarized the main components of hydrogel in periodontal tissue regeneration and have discussed the primary construction strategies of hydrogels as a reference for future work. Hydrogels provide an ideal microenvironment for cells and play a significant role in periodontal tissue engineering. The development of intelligent and multifunctional hydrogels for periodontal tissue regeneration is essential for future research.

Topics & Concepts

Self-healing hydrogelsRegeneration (biology)Tissue engineeringExtracellular matrixBiocompatibilityMaterials scienceNanotechnologyBiomedical engineeringMedicineCell biologyBiologyMetallurgyPolymer chemistryOral microbiology and periodontitis researchProteoglycans and glycosaminoglycans researchPeriodontal Regeneration and Treatments