Autophagy inhibition by targeting PIKfyve potentiates response to immune checkpoint blockade in prostate cancer
Yuanyuan Qiao, Jae Eun Choi, Jean C. Tien, Stephanie A. Simko, Thekkelnaycke M. Rajendiran, Josh N. Vo, Andrew Delekta, Lisha Wang, Lanbo Xiao, Nathan Hodge, Parth Desai, Sergio Mendoza, Kristin Juckette, Alice Xu, Tanu Soni, Fengyun Su, Rui Wang, Xuhong Cao, Jiali Yu, Ilona Kryczek, Xiao Ming Wang, Xiaoju Wang, Javed Siddiqui, Zhen Wang, Amélie Bernard, Ester Fernández‐Salas, Nora M. Navone, Stephanie J. Ellison, Ke Ding, Eeva‐Liisa Eskelinen, Elisabeth I. Heath, Daniel J. Klionsky, Weiping Zou, Arul M. Chinnaiyan
Topics & Concepts
Cancer researchAutophagyImmune checkpointTumor microenvironmentImmune systemBlockadeProstate cancerBiologyMedicineImmunotherapyCancerImmunologyApoptosisReceptorInternal medicineBiochemistryAutophagy in Disease and TherapyImmunotherapy and Immune ResponsesUbiquitin and proteasome pathways