HIF-1alpha/VEGF pathway mediates 1,3,6,8-tetrabromo-9 H-carbazole-induced angiogenesis: a potential vascular toxicity of an emerging contaminant
Tong Xu, Xiaoxu Hu, Guanglei Yang, Yiyun Liu, Qian Zhang, Shuyuan Yu, Guomin Chen, Yunping Li, Rui Sha, Yangsheng Chen, Heidi Qunhui Xie, Tai L. Guo, Li Xu, Bin Zhao
Topics & Concepts
Aryl hydrocarbon receptorAngiogenesisHypoxia-inducible factorsTransfectionVascular endothelial growth factorAryl hydrocarbon receptor nuclear translocatorSignal transductionBiologyDownregulation and upregulationCell biologyUmbilical veinKinase insert domain receptorVascular endothelial growth factor ACancer researchChemistryPharmacologyTranscription factorBiochemistryVEGF receptorsGeneIn vitroCancer, Hypoxia, and MetabolismEicosanoids and Hypertension PharmacologyAdipose Tissue and Metabolism