Genomic Drivers of Multidrug-Resistant <i>Shigella</i> Affecting Vulnerable Patient Populations in the United States and Abroad
Jay Worley, Kiran Javkar, Maria Hoffmann, Kristen Hysell, Amanda G. Garcia‐Williams, Kaitlin A. Tagg, Sanjat Kanjilal, Errol Strain, Mihai Pop, Marc W. Allard, Louise Francois Watkins, Lynn Bry
Abstract
Multidrug-resistant Shigella isolates with resistance to macrolides are an emerging public health threat. We define a plasmid/pathogen complex behind infections seen in the United States and globally in vulnerable patient populations and identify multiple outbreaks in the United States and evidence of intercontinental transmission.
Topics & Concepts
OutbreakShigellaMultiple drug resistanceShigellosisTransmission (telecommunications)PathogenPublic healthBiologyPlasmidEnvironmental healthMicrobiologyVirologyMedicineDrug resistanceGeneticsGeneBacteriaSalmonellaTelecommunicationsComputer scienceNursingEscherichia coli research studiesViral gastroenteritis research and epidemiologySalmonella and Campylobacter epidemiology