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Saponin and hexanal in pea (Pisum sativum) protein isolates: A comparative study of isoelectric precipitation and ultrafiltration

Hartono Tanambell, Mille Raabjerg Bramsen, Marianne Danielsen, Caroline Nebel, Anders Hauer Møller, Trine Kastrup Dalsgaard

2025LWT6 citationsDOIOpen Access PDF

Abstract

Yellow pea is considered as a promising source of dietary protein due to its low carbon footprint and adaptability to temperate climates. However, off-flavor compounds such as saponins and hexanal maabsy hinder consumer acceptance. This study investigated how pea protein purification methods influenced saponin and hexanal co-concentration in resulting isolates. High resolution mass spectrometry (MS) identified soyasaponins I and VI as the only saponins in pea flour. Heating saponin extracts at 90 °C converted soyasaponin VI to I, enabling quantification using triple quadrupole MS. Hexanal was extracted by headspace solid phase microextraction and analyzed using gas chromatography-MS. Protein isolates were produced through wet extraction and isoelectric precipitation or ultrafiltration-diafiltration. Isoelectric precipitation (88.03±0.47% protein) concentrated saponins by ∼3-fold, while reducing hexanal by ∼6 times, relative to pea flour. A washing step after isoelectric precipitation (96.92±2.19% protein) further increased saponin concentration by ∼34% but did not affect hexanal. Ultrafiltration-diafiltration using a 30 kDa membrane yielded isolates (78.91±1.90% protein) with saponin and hexanal content similar to pea flour, regardless of salt extraction (79.05±3.30% protein). Although isoelectric precipitation resulted in higher protein purity, gel electrophoresis showed minimal differences in protein profiles. These findings highlight that processing influences off-flavor compounds retention in pea protein ingredients.

Topics & Concepts

SativumPisumHexanalIsoelectric pointUltrafiltration (renal)SaponinPea proteinIsoelectric focusingChromatographyBiologyChemistryBotanyBiochemistryEnzymeMedicinePathologyAlternative medicineFood composition and propertiesProteins in Food SystemsMicrobial Metabolites in Food Biotechnology
Saponin and hexanal in pea (Pisum sativum) protein isolates: A comparative study of isoelectric precipitation and ultrafiltration | Litcius