Current and Future Management of Locally Advanced and Metastatic Prostate Cancer.
Neal D. Shore
Abstract
With increasing treatment options available, the management of locally advanced and metastatic prostate cancer (PCa) is growing more complex, nuanced, and individualized. Strategies for combining surgery, radiation, chemotherapy, and androgen deprivation therapy (ADT) continue to evolve, as do ADT and immunotherapy options. Additionally, multiple adjunctive agents for metastatic PCa have been recently approved or are pending approval. As the number of locally advanced and metastatic prostate cancers being diagnosed rises, so does the need to consider patients' clinical situations and personal preferences. This review discusses current and potential future approaches to managing locally advanced and metastatic PCa.
Topics & Concepts
MedicineProstate cancerManagement of prostate cancerRadiation therapyOncologyAndrogen deprivation therapyImmunotherapyInternal medicineIntensive care medicineCancerProstate Cancer Treatment and ResearchProstate Cancer Diagnosis and TreatmentCancer, Lipids, and Metabolism