Study of Cytotoxic and Antibacterial Activity of Ag‐ and Mg‐Dual‐Doped ZnO Nanoparticles
Aytan Azizi, Mohammad Ghasemirad, Bardia Mortezagholi, Emad Movahed, Seyed Sasan Aryanezhad, Ali Makiya, Hoda Ghodrati, Kamyar Nasiri
Abstract
A non-laborious process for the fabrication of silver and magnesium dual doped zinc oxide nanoparticles (Ag/Mg-ZnO NP) is described. The wurtzite ZnO nano-structures and the dual doped NP were analyzed by PXRD. SEM data showed the hexagonal morphology of our product, while the gathered anti-bacterial outcomes towards Streptococcus mutans bacteria through micro-dilution technic affirmed the enhanced performance of doped NP compared to the native ones. Furthermore, we gauged the toxic impacts of synthesized pure and Ag/Mg-ZnO NP against a breast cancer (MDA-MB-231) cell line through an MTT trial, which highlighted the superiority of the doped when compared to the native nanoparticles. In light of these comparisons, the applicability of Ag/Mg-ZnO NP in dental and medical science is proposed.