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New codons for efficient production of unnatural proteins in a semisynthetic organism

Emil C. Fischer, Koji Hashimoto, Yorke Zhang, Aaron W. Feldman, Vivian T. Dien, Rebekah J. Karadeema, Ramkrishna Adhikary, Michael P. Ledbetter, Ramanarayanan Krishnamurthy, Floyd E. Romesberg

2020Nature Chemical Biology106 citationsDOIOpen Access PDF

Topics & Concepts

Genetic codeStop codonTransfer RNAAmino acidBiologyReading frameRibosomeCodon usage biasTranslation (biology)Computational biologyOrganismGeneticsProtein biosynthesisBase pairGeneOpen reading frameRNAPeptide sequenceGenomeMessenger RNARNA and protein synthesis mechanismsBacterial Genetics and BiotechnologyChemical Synthesis and Analysis
New codons for efficient production of unnatural proteins in a semisynthetic organism | Litcius