Mechanochemical Conversion of Aromatic Amines to Aryl Trifluoromethyl Ethers
Michał Jakubczyk, Satenik Mkrtchyan, Mohanad Shkoor, Suneel Lanka, Šimon Budzák, Miroslav Iliaš, Marek Skoršepa, Viktor O. Iaroshenko
Abstract
Ar products were obtained in excellent yields. The presented concise method opens a pathway to new chemical spaces for the pharmaceutical industry.
Topics & Concepts
ChemistryNucleophilic aromatic substitutionTrifluoromethylArylRing (chemistry)TetrafluoroborateOrganic chemistryScope (computer science)Combinatorial chemistryElectrophilic aromatic substitutionGroup (periodic table)Ionic liquidNucleophilic substitutionCatalysisAlkylComputer scienceProgramming languageFluorine in Organic ChemistryChemical Synthesis and AnalysisSynthesis and Reactions of Organic Compounds