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The Role of Whole Blood Transfusions in Civilian Trauma: A Review of Literature in Military and Civilian Trauma

Shane Kronstedt, Joon Lee, David Millner, Connor L. Mattivi, Halli LaFrankie, Lorenzo Paladino, Jeffrey Siegler

2022Cureus15 citationsDOIOpen Access PDF

Abstract

Resuscitation techniques for the management of adult trauma patients have evolved over the 20th century. Whole blood transfusions were previously used as the standard of care, whereas blood component therapy is the current method employed across most trauma centers across the United States. Prior to the transition, no studies were conducted to show improved efficacy of hemostatic potential in trauma patients. Recent conflicts in Iraq and Afghanistan have challenged the dogma that whole blood transfusions are not the standard of care and have shown potential as the superior transfusion product for adult trauma patients. The purpose of this review is to provide a comprehensive review and elucidate if whole blood transfusions have a role in civilian trauma patients based upon recent military medical literature and civilian pilot studies using whole blood transfusions.

Topics & Concepts

MedicineWhole bloodIntensive care medicineResuscitationTrauma careBlood componentBlood transfusionBlood productStandard of careEmergency medicineMilitary medicineMedical emergencySurgeryLawPolitical scienceTrauma, Hemostasis, Coagulopathy, ResuscitationTrauma and Emergency Care StudiesBlood transfusion and management
The Role of Whole Blood Transfusions in Civilian Trauma: A Review of Literature in Military and Civilian Trauma | Litcius