Identification of proteasome and caspase inhibitors targeting SARS-CoV-2 Mpro
Zhengyuan Wang, Yao Zhao, Qingxing Wang, Yangfei Xing, Lu Feng, Juan Kong, Chao Peng, Leike Zhang, Haitao Yang, Min Lü
Topics & Concepts
ProteasomeSevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2)Coronavirus disease 2019 (COVID-19)Identification (biology)Computational biology2019-20 coronavirus outbreakVirologyCaspaseBiologyMedicineApoptosisBiochemistryPathologyProgrammed cell deathDiseaseInfectious disease (medical specialty)BotanyOutbreakSARS-CoV-2 and COVID-19 Researchinterferon and immune responsesCell death mechanisms and regulation