Synergistic immunotherapy with a calcium-based nanoinducer: evoking pyroptosis and remodeling tumor-associated macrophages for enhanced antitumor immune response
Fang Cheng, Lei He, Jiaqi Wang, Lunhui Lai, Li Ma, Kuiming Qu, Zicheng Yang, Xinyue Wang, Ruyu Zhao, Lixing Weng, Lianhui Wang
Abstract
T cell-dependent systemic antitumor immunity. Our study presents a promising synergistic strategy for achieving highly efficient immunotherapy using a simple calcium-based nanoinducer.
Topics & Concepts
PyroptosisImmunosuppressionImmune systemImmunotherapyCancer researchImmunityImmunologyCalciumMedicineInflammationInternal medicineInflammasomePhagocytosis and Immune RegulationImmune cells in cancerNanoplatforms for cancer theranostics