A New Tool for CRISPR-Cas13a-Based Cancer Gene Therapy
Jinliang Gao, Tao Luo, Na‐Sheng Lin, Shuyan Zhang, Jinke Wang
Abstract
and the xenografted Hepa1-6 and WEHI-3 tumors in mice. This study therefore developed a new tool for the CRISPR-Cas13a-based cancer gene therapy.
Topics & Concepts
RNA interferenceGenetic enhancementTransfectionCRISPRHEK 293 cellsAdeno-associated virusBiologyCancer researchGeneGene expressionCancerMolecular biologyCancer cellApoptosisDecoyRNAVector (molecular biology)Recombinant DNAGeneticsReceptorCRISPR and Genetic EngineeringVirus-based gene therapy researchRNA Interference and Gene Delivery