Benzylic C(sp<sup>3</sup>)–C(sp<sup>2</sup>) cross-coupling of indoles enabled by oxidative radical generation and nickel catalysis
Weonjeong Kim, Jangwoo Koo, Hong Geun Lee
Abstract
)-based reaction counterparts. Mechanistic studies have shown that competitive hydrogen atom transfer (HAT) processes, which are frequently encountered in conventional methods, are not involved in the product formation process of the developed strategy.
Topics & Concepts
ChemoselectivityCatalysisNickelSubstrate (aquarium)ChemistryCombinatorial chemistryScope (computer science)Coupling (piping)StereochemistryOrganic chemistryMaterials scienceComputer scienceGeologyOceanographyMetallurgyProgramming languageCatalytic C–H Functionalization MethodsRadical Photochemical ReactionsSulfur-Based Synthesis Techniques