CTPS1 is a novel therapeutic target in multiple myeloma which synergizes with inhibition of CHEK1, ATR or WEE1
Christina Pfeiffer, Alexander M. Grandits, Hélène Asnagli, Anja Schneller, Julia Huber, Niklas Zojer, Martin Schreder, Andrew E. Parker, Arnold Bolomsky, Philip Beer, Heinz Ludwig
Topics & Concepts
Wee1DNA damageApoptosisCHEK1Cancer researchBiologyGrowth inhibitionCell cycle checkpointCell cycleCyclin-dependent kinase 1DNABiochemistryBiochemical and Molecular ResearchHIV/AIDS drug development and treatmentPneumocystis jirovecii pneumonia detection and treatment