Metabolic reprogramming of terminally exhausted CD8+ T cells by IL-10 enhances anti-tumor immunity
Yugang Guo, Yuqing Xie, Min Gao, Yang Zhao, Fabien Franco, Mathias Wenes, Imran Siddiqui, Alessio Bevilacqua, Haiping Wang, Hanshuo Yang, Bing Feng, Xin Xie, Catherine Sabatel, Benjamin Tschumi, Amphun Chaiboonchoe, Yuxi Wang, Weimin Li, Weihua Xiao, Werner Held, Pedro Romero, Ping‐Chih Ho, Li Tang
Topics & Concepts
Cytotoxic T cellCD8ImmunotherapyReprogrammingCancer immunotherapyCancer researchT cellAdoptive cell transferBiologyEffectorImmune systemImmunologyCell biologyCellBiochemistryIn vitroCAR-T cell therapy researchCancer Research and TreatmentsCancer Immunotherapy and Biomarkers