The GIANT trial (ECOG-ACRIN EA2186) methods paper: A randomized phase II study of gemcitabine and nab-paclitaxel compared with 5-fluorouracil, leucovorin, and liposomal irinotecan in older patients with treatment-naïve metastatic pancreatic cancer - defining a new treatment option for older vulnerable patients

Efrat Dotan, Paul J. Catalano, Leon Lenchik, Robert D. Boutin, Xin Yao, Helga S. Marques, Dina Ioffe, David B. Zhen, Daneng Li, Lynne I. Wagner, Melissa A. Simon, Terence Z. Wong, Peter J. O’Dwyer