Litcius/Paper detail

Controversies over hydroxychloroquine in the prevention of SARS-CoV-2 infection put rheumatologists on the frontline

Serena Bugatti, Ludovico De Stefano, Francesca Bobbio‐Pallavicini, Carlomaurizio Montecucco

2020RMD Open54 citationsDOIOpen Access PDF

Abstract

The outburst of the novel COVID-19 has caused unprecedented stress in the healthcare systems and global economy since its outbreak in December 2019. Effective treatment for severely ill patients still needs to be identified, and many countries are still pushed by daily increases in case numbers and deaths. Furthermore, before a vaccine is made available or drugs eventually capable of preventing the infection are identified, exit strategies in those countries that have managed to bend the transmission curve are inevitably governed by trial and error. The alarm remains high also because COVID-19 flare-ups are increasingly likely and a second wave in fall is seen as a real risk.

Topics & Concepts

MedicineHydroxychloroquineCytokine stormIntensive care medicineTransmission (telecommunications)Clinical trialCoronavirus disease 2019 (COVID-19)Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)ImmunologyInternal medicineDiseaseInfectious disease (medical specialty)EngineeringElectrical engineeringCOVID-19 Clinical Research StudiesSARS-CoV-2 and COVID-19 ResearchLong-Term Effects of COVID-19