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Integration of single-cell and bulk RNA sequencing data using machine learning identifies oxidative stress-related genes LUM and PCOLCE2 as potential biomarkers for heart failure

Chaofang Li, Ruyi Hao, Chuanfu Li, Li Jun Liu, Zhengnian Ding

2025International Journal of Biological Macromolecules20 citationsDOI

Topics & Concepts

Oxidative stressHeart failureGeneRNAComputational biologyCellBiologyBioinformaticsGeneticsMedicineInternal medicineBiochemistryAtherosclerosis and Cardiovascular DiseasesSingle-cell and spatial transcriptomicsCardiac Fibrosis and Remodeling
Integration of single-cell and bulk RNA sequencing data using machine learning identifies oxidative stress-related genes LUM and PCOLCE2 as potential biomarkers for heart failure | Litcius