A near-complete genome assembly of Catharanthus roseus and insights into its vinblastine biosynthesis and high susceptibility to the Huanglongbing pathogen
Zhongping Xu, Guanying Wang, Qiongqiong Wang, Xiaoting Li, Guangyu Zhang, Ali Qurban, Can Zhang, Yi Zhou, Huan Si, Lisong Hu, Fuqiu Wang, Ying Wang, Zhitao Tian, Wei Chen, Shuangxia Jin, Fang Ding
Abstract
This study reports the assembly of a near-complete genome of Catharanthus roseus, consisting of 561.7 Mb scaffolded into 8 pseudochromosomes with a contig N50 of 24.7 Mb and a scaffold N50 of 71.1 Mb. The assembly enables the construction of a gene regulatory network of the vinblastine biosynthetic pathway and provides insights into the high susceptibility of C. roseus to the Huanglongbing pathogen.
Topics & Concepts
Catharanthus roseusContigBiologyGenomeSequence assemblyGeneVinblastinePathogenGeneticsComputational biologyBotanyTranscriptomeGene expressionChemotherapyPhytoplasmas and Hemiptera pathogensPlant Pathogenic Bacteria StudiesPlant Virus Research Studies