Navigated Delivery of Peptide to the Nanopore Using In-Plane Heterostructures of MoS<sub>2</sub> and SnS<sub>2</sub> for Protein Sequencing
Wei Si, Runyi Yuan, Gensheng Wu, Yajing Kan, Jingjie Sha, Yunfei Chen, Yin Zhang, Yang Shen
Abstract
heterostructure. Through switching the direction of the applied electric field in real time, the peptide was strategically driven to move along the designed path to the target nanopore. The ionic current blockades were also found to be different as the compositions of the peptide were changed, indicating the possibility for differentiating different peptides using this platform.
Topics & Concepts
NanoporePeptideNanopore sequencingNanotechnologyAffinitiesElectric fieldMaterials scienceNanobiotechnologyBiophysicsChemistryDNA sequencingDNABiologyPhysicsBiochemistryNanoparticleQuantum mechanicsNanopore and Nanochannel Transport StudiesAdvanced biosensing and bioanalysis techniquesIon-surface interactions and analysis