Chiral Plasmonic Nanoparticle Assisted Raman Enantioselective Recognition
Xueping Sun, Huanjun Kong, Qinghai Zhou, Seiji Tsunega, Xinling Liu, Haifeng Yang, Ren‐Hua Jin
Abstract
Au nanoparticles (NPs) labeled with the handedness tag of "d-" or "l-", which were detached from inorganic chiral silica, showed both intrinsic chirality and surface enhanced Raman scattering (SERS) activity. In the presence of these chiral Au substrates, it was found that the enantiomer of cystine with the same handedness tag of Au NPs would show stronger Raman scattering signal intensities than those of the enantiomer with the opposite tag, where the differences could be over three times. Consequently, this work afforded a novel enantioselective recognition method on ordinary Raman spectroscopy by using chiral plasmonic metallic nanomaterials.
Topics & Concepts
ChemistryEnantioselective synthesisRaman spectroscopyRaman scatteringChirality (physics)NanoparticlePlasmonEnantiomerRaman optical activityNanomaterialsPlasmonic nanoparticlesNanotechnologyMoleculeStereochemistryOrganic chemistryCatalysisOpticsOptoelectronicsMaterials scienceQuantum mechanicsChiral symmetry breakingQuarkPhysicsNambu–Jona-Lasinio modelGold and Silver Nanoparticles Synthesis and ApplicationsNanocluster Synthesis and ApplicationsAdvanced biosensing and bioanalysis techniques