Synthesis of new Fe(III), Co(II), and Cr(III) complexes of <i>N</i>‐(benzo[<i>d</i>]thiazol‐2‐ylcarbamothioyl)benzamide (H<sub>2</sub>L<sub>2</sub>): Structural characterization and biological activities
Eida S. Al‐Farraj, Ahmed Fetoh
Abstract
N ‐(benzo[ d ]thiazol‐2‐ylcarbamothioyl)benzamide (H 2 L 2 ) was synthesized as a novel thiosemicarbazide containing benzothiazole moiety, by the reaction of benzoyl isothiocyanate with 2‐aminobenzothiazole in benzene. The (H 2 L 2 ) thiosemicarbazide and its isolated Cr(III), Fe(III), and Co(II) complexes were fully analyzed by different spectroscopic techniques. The thermal fragmentation of [Cr (HL 2 )Cl 2 (H 2 O) 2 ].10H 2 O, [Co (HL 2 )Cl(H 2 O) 2 ].6H 2 O, and [Fe(L 2 )Cl(H 2 O) 2 ] were analyzed. We have also calculated the thermal parameters with using two different methods. The ligand undergoes tranamidation in the presence of PdCl 2 . Crystal structure of the product obtained by tranamidation is measured. Biological activities of those compounds were assessed as antioxidants, anticancer, and antimicrobial.