Synthesis and Photochemical Application of Hydrofluoroolefin (HFO) Based Fluoroalkyl Building Block
Bálint Varga, Balázs L. Tóth, Ferenc Béke, János T. Csenki, András Kotschy, Zoltán Novàk
Abstract
A novel fluoroalkyl iodide was synthesized on multigram scale from refrigerant gas HFO-1234yf as cheap industrial starting material in a simple, solvent-free, and easily scalable process. We demonstrated its applicability in a metal-free photocatalytic ATRA reaction to synthesize valuable fluoroalkylated vinyl iodides and proved the straightforward transformability of the products in cross-coupling chemistry to obtain conjugated systems.
Topics & Concepts
ChemistryRefrigerantIodideBlock (permutation group theory)SolventPhotocatalysisCombinatorial chemistryConjugated systemOrganic chemistryPolymerCatalysisGeometryMechanical engineeringEngineeringGas compressorMathematicsFluorine in Organic ChemistryOxidative Organic Chemistry ReactionsInorganic Fluorides and Related Compounds