Esculin inhibits hepatic stellate cell activation and CCl4-induced liver fibrosis by activating the Nrf2/GPX4 signaling pathway
Shuoxi Xu, Yonger Chen, Jindian Miao, Yuhua Li, Jiaying Liu, Jing Zhang, Jian Liang, Shuxian Chen, Shaozhen Hou, Shaozhen Hou
Topics & Concepts
Hepatic stellate cellTraditional medicineBark (sound)PharmacologyCCL4Liver fibrosisFibrosisTaxifolinChemistryAntioxidantBiologyMedicineBiochemistryPathologyCarbon tetrachlorideFlavonoidOrganic chemistryEcologyLiver physiology and pathologyLiver Disease Diagnosis and TreatmentGenomics, phytochemicals, and oxidative stress