DAF-16 acts as the “hub” of astaxanthin's anti-aging mechanism to improve aging-related physiological functions in <i>Caenorhabditis elegans</i>
Xiaojuan Liu, Han Liu, Zhiqing Chen, Jie Xiao, Yong Cao
Abstract
This study measured the effects of AX on the longevity and physiological indexes of C. elegans under different conditions, and explored the possible anti-aging mechanism of AX by analyzing aging proteins and signaling pathways through proteomics.
Topics & Concepts
Caenorhabditis elegansCell biologyBiologySignal transductionInsulin receptorOxidative stressHeat shock proteinBiochemistryInsulinInsulin resistanceGeneEndocrinologyGenetics, Aging, and Longevity in Model OrganismsCircadian rhythm and melatoninCoenzyme Q10 studies and effects