Triglyceride/High‐Density Lipoprotein Cholesterol Ratio Is Associated with In‐Hospital Mortality in Acute Type B Aortic Dissection
Yang Zhou, Guifang Yang, Huaping He, Xiaogao Pan, Wen Peng, Xiangping Chai
Abstract
Background . Triglyceride/high‐density lipoprotein cholesterol (TG/HDL‐c) ratio varies with vascular and other metabolic diseases. However, its role in acute type B aortic dissection is not well understood. In the current study, we evaluated the relationship between TG/HDL‐c ratio and in‐hospital mortality in type B aortic dissection. Methods . We performed a retrospective analysis of consecutive patients between January 2015 and December 2018, by targeting dependent (TG/HDL‐c ratio) and independent (in‐hospital mortality) variables. TG/HDL‐c ratio was determined as a division of TG levels by HDL‐c levels. Results . Of 523 patients in the study, we found a mean age of 55.00 ± 11.74 years, 15.68% of them being female. A fully‐adjusted model revealed a positive relationship between TG/HDL‐c ratio and in‐hospital mortality in acute type B aortic dissection after adjusting confounders (OR = 2.08, 95% CI 1.32 to 3.27). This relationship was also nonlinear, with a point of 2.05. OR values (and confidence intervals) for the right (>2.05) and left (≤2.05) sides of the inflection point were 1.0 (0.580‐1.26, P = 0.983) and 3.17 (1.54‐6.57, P = 0.001), respectively. Conclusions . The TG/HDL‐c ratio and in‐hospital mortality in type B AAD have a nonlinear relationship among Chinese population. This ratio increased in‐hospital mortality when it is less than 2.05.