DDIT3/CHOP promotes autophagy in chondrocytes via SIRT1-AKT pathway
Chang Yang, Xiaoxiao Xu, Xiaofei Dong, Beining Yang, Wei Dong, Yao Luo, Xiayi Liu, Yanru Wu, Jiawei Wang
Topics & Concepts
AutophagyCHOPGene knockdownPI3K/AKT/mTOR pathwayProtein kinase BCell biologyUnfolded protein responseSignal transductionWestern blotBiologyEndoplasmic reticulumCancer researchCell cultureApoptosisBiochemistryGeneticsGeneAutophagy in Disease and TherapyEndoplasmic Reticulum Stress and DiseaseSirtuins and Resveratrol in Medicine