Baicalin induces ferroptosis in osteosarcomas through a novel Nrf2/xCT/GPX4 regulatory axis
Ruijia Wen, Xin Dong, Haowen Zhuang, Feng-xiang Pang, Shou-chang Ding, Nan Li, Yongxin Mai, Shuting Zhou, Junyan Wang, Jinfang Zhang
Topics & Concepts
BaicalinChemistryCell biologyGPX4PharmacologyCancer researchBiologyBiochemistryAntioxidantSuperoxide dismutaseHigh-performance liquid chromatographyChromatographyGlutathione peroxidaseFerroptosis and cancer prognosisCancer-related molecular mechanisms researchClusterin in disease pathology