Litcius/Paper detail

Programmable Solid-State [2 + 2] Photocycloadditions of Dienes Directed by Structural Control and Wavelength Selection

Liulei Ma, Gary C. George, Steven P. Kelley, Kristin M. Hutchins

2025Journal of the American Chemical Society16 citationsDOI

Abstract

)-2-bromostyryl)benzene (2Brm), is synthesized and crystallized into two unique solid-state forms, each exhibiting a different π-π stacking geometry, which imparts distinct reactivity and photoresponsivity. Upon exposure of the two solids to UV-Vis light, a [2 + 2] photocycloaddition occurs to afford regioisomeric products due to the difference in the stacking geometries of the dienes. From a single molecular precursor, we further demonstrate that under different wavelengths of light, the chemical functionality can be programmed into discrete and distinct products containing one, two, or three cyclobutane rings as well as oligomeric/polymeric products. Moreover, the two initial solid forms exhibit wavelength-dependent photomechanical behaviors (i.e., photosalience). This work demonstrates a rare, template-free, self-assembly-based strategy that enables access to a suite of discrete and oligomeric/polymeric products via regiocontrolled solid-state photocycloadditions and further presents potential routes toward the design of photoactuating materials.

Topics & Concepts

ChemistrySelection (genetic algorithm)WavelengthSolid-stateOptoelectronicsPhysical chemistryArtificial intelligencePhysicsComputer sciencePhotochromic and Fluorescence ChemistryCrystallography and molecular interactionsRadical Photochemical Reactions