Enantioselective nickel-catalyzed <i>anti</i>-arylmetallative cyclizations onto acyclic electron-deficient alkenes
Simone M. Gillbard, Harley Green, Stephen P. Argent, Hon Wai Lam
Abstract
Enantioselective nickel-catalyzed reactions of (hetero)arylboronic acids or alkenylboronic acids with substrates containing an alkyne tethered to various acyclic electron-deficient alkenes are described.
Topics & Concepts
Enantioselective synthesisNickelCatalysisAlkyneChemistryCombinatorial chemistryAlkeneOrganic chemistryStereochemistryCatalytic C–H Functionalization MethodsCatalytic Alkyne ReactionsCyclopropane Reaction Mechanisms