Test of Rapamycin in Aging Dogs (TRIAD): study design and rationale for a prospective, parallel-group, double-masked, randomized, placebo-controlled, multicenter trial of rapamycin in healthy middle-aged dogs from the Dog Aging Project

Amanda E. Coleman, Kate E. Creevy, Rozalyn M. Anderson, May J. Reed, Virginia R. Fajt, Kathleen M. Aicher, Genna Atiee, Brian Barnett, Ryan Baumwart, Beth Boudreau, Suzanne M. Cunningham, Matthew D. Dunbar, Bobbie Ditzler, A. P. Ferguson, Kiersten K. Forsyth, Anya N. Gambino, Sonya G. Gordon, Hillary K. Hammond, Sydney Holland, Mario Iannaccone, Kate Illing, Saki Kadotani, Shelby A. Knowles, Evan L. MacLean, B.A. Maran, Lauren E. Markovic, Stephanie McGrath, Rachel L. Melvin, Mikaela S. Mueller, O. Lynne Nelson, Natasha J. Olby, Theresa E. Pancotto, Elizabeth Parsley, Brianna M. Potter, Jena O. Prescott, Ashley B. Saunders, H. Sawyer, Brian A. Scansen, S Schmid, Courtney C. Smith, Sonja S. Tjostheim, M. Katherine Tolbert, Melissa A. Tropf, Lance C. Visser, Jessica Ward, S. Wesselowski, Rebecca Windsor, Vicky K. Yang, Audrey Ruple, Daniel Promislow, Matt Kaeberlein, Joshua M. Akey, Brooke Benton, Elhanan Borenstein, Marta G. Castelhano, Amanda E. Coleman, Kate E. Creevy, Annette L. Fitzpatrick, Kyle Crowder, Matthew D. Dunbar, Virginia R. Fajt, Annette L. Fitzpatrick, Unity Jeffery, Erica C. Jonlin, Matt Kaeberlein, Elinor K. Karlsson, Kathleen F. Kerr, Jonathan M. Levine, Jing Ma, Robyn L. McClelland, Daniel E. L. Promislow, Audrey Ruple, Stephen M. Schwartz, Sandi Shrager, Noah M. Snyder-Mackler, M. Katherine Tolbert, Silvan R. Urfer, Benjamin S. Wilfond