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Controlled bioorthogonal activation of Bromodomain-containing protein 4 degrader by co-delivery of PROTAC and Pd-catalyst for tumor-specific therapy

Zhiyao Li, Tai‐Bai Jiang, Yuan Xu, Bowen Li, Chongzhi Wu, Yecheng Li, Yong Huang, Xin Xie, Weidong Pan, Ping Yuan

2024Journal of Controlled Release19 citationsDOI

Topics & Concepts

Bioorthogonal chemistryProdrugChemistryCatalysisCombinatorial chemistryPhotothermal therapyDrug deliveryBiochemistryNanotechnologyOrganic chemistryMaterials scienceClick chemistryProtein Degradation and InhibitorsUbiquitin and proteasome pathwaysPeptidase Inhibition and Analysis
Controlled bioorthogonal activation of Bromodomain-containing protein 4 degrader by co-delivery of PROTAC and Pd-catalyst for tumor-specific therapy | Litcius