Exogenous hydrogen sulfide inhibits neutrophils extracellular traps formation via the HMGB1/TLR4/p-38 MAPK/ROS axis in hyperhomocysteinemia rats
Xueying Zhao, Liyuan Zhang, Xin Liu, Ziqing Zhao, Xin Zhong, Yuwen Wang
Topics & Concepts
ChemistryHyperhomocysteinemiap38 mitogen-activated protein kinasesSodium hydrosulfideReactive oxygen speciesTLR4PlateletHMGB1ExtracellularHomocysteineHydrogen sulfideMolecular biologyBiochemistryMAPK/ERK pathwaySignal transductionInternal medicineSulfurBiologyReceptorMedicineOrganic chemistryNeutrophil, Myeloperoxidase and Oxidative MechanismsEosinophilic Disorders and SyndromesMast cells and histamine