Photoinduced C–O bond cleavage for copper-catalyzed allenyl radical cyanation
Fu‐Dong Lu, Zhen‐Cao Shu, Gui-Feng He, Jun-Chuan Bai, Liang‐Qiu Lu, Wen‐Jing Xiao
Abstract
The synthesis of allenyl nitriles was realized through the combination of photoinduced C–O bond cleavage and copper catalysis. Both 1,3-disubstituted and trisubstituted allenyl nitriles were accessed with good yields and high regioselectivity.
Topics & Concepts
CyanationChemistryRegioselectivityBond cleavageCleavage (geology)CopperCatalysisMedicinal chemistryPhotochemistryCombinatorial chemistryPolymer chemistryOrganic chemistryEngineeringFracture (geology)Geotechnical engineeringRadical Photochemical ReactionsSulfur-Based Synthesis TechniquesCatalytic C–H Functionalization Methods