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Exploring efficacy of indole-based dual inhibitors for α-glucosidase and α-amylase enzymes: In silico, biochemical and kinetic studies

Abdel‐Nasser Kawde, Muhammad Taha, Raneem Saud Alansari, Noor B. Almandil, El Hassane Anouar, Nizam Uddin, Fazal Rahim, Sridevi Chigurupati, Muhammad Nawaz, Shawkat Hayat, Mohamad Ibrahim, Praveen Kumar Elakurthy, Vijayan Venugopal, Mohamed A. Morsy, Hossieny Ibrahim, Nadeem Baig, Khalid Mohammed Khan

2020International Journal of Biological Macromolecules38 citationsDOI

Topics & Concepts

AcarboseChemistryEnzymeAmylaseIC50In silicoIndole testReducing sugarSugarMacromoleculeBiochemistrySmall moleculeAlpha-glucosidaseAlpha-amylaseDocking (animal)StereochemistryIn vitroMedicineGeneNursingNatural Antidiabetic Agents StudiesDiet, Metabolism, and DiseaseAdvanced Glycation End Products research
Exploring efficacy of indole-based dual inhibitors for α-glucosidase and α-amylase enzymes: In silico, biochemical and kinetic studies | Litcius