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Giant Coronary Aneurysms in Multisystem Inflammatory Syndrome in Children Associated With SARS-CoV-2 Infection

D. Sofia Villacis-Nunez, Sassan Hashemi, Meghan Corrigan Nelson, Elaine Flanagan, Amit Thakral, Fred H. Rodriguez, Preeti Jaggi, Matthew E. Oster, Sampath Prahalad, Kelly Rouster‐Stevens

2021JACC Case Reports24 citationsDOIOpen Access PDF

Abstract

Multisystem inflammatory syndrome in children (MIS-C) can cause a myriad of cardiac manifestations, including coronary dilation and aneurysms; giant aneurysms are infrequent. We describe 3patients with giant coronary aneurysms associated with MIS-C, including the youngest case reported to date, treated with intravenous immunoglobulin, corticosteroids, and biologic agents. (Level of Difficulty: Intermediate.)

Topics & Concepts

MedicineAneurysmCoronavirus disease 2019 (COVID-19)AntibodyCardiologyInternal medicineImmunologySurgeryDiseaseInfectious disease (medical specialty)Kawasaki Disease and Coronary ComplicationsCoronary Artery AnomaliesCardiovascular Issues in Pregnancy
Giant Coronary Aneurysms in Multisystem Inflammatory Syndrome in Children Associated With SARS-CoV-2 Infection | Litcius