Single-Cell Heterogeneity of the Liver-Infiltrating Lymphocytes in Individuals with Chronic Echinococcus multilocularis Infection
Tiemin Jiang, Wujianan Sun, Tuerganaili Aji, Yingmei Shao, Chuang Guo, Chuanshan Zhang, Bo Ran, Jiao Hou, Aimaiti Yasen, Qiang Guo, Hui Wang, Kun Qu, Hao Wen
Abstract
T cells and iTregs or Th17 cells, especially for genes related to immunosuppression, such as PDCD1-FAM3C, which were highly expressed in PL tissue. This transcriptional data set provides valuable insights and a rich resource for deeply understanding the immune microenvironment in AE, which could provide potential target signatures for AE diagnosis and immunotherapies.
Topics & Concepts
Echinococcus multilocularisBiologyCestodaImmunologyChronic infectionEchinococcusHelminthiasisCestode infectionsVirologyEchinococcosisHelminthsImmune systemZoologyParasitic infections in humans and animalsCongenital Anomalies and Fetal SurgeryParasitic Infections and Diagnostics