Hydnocarpin D attenuates lipopolysaccharide-induced acute lung injury via MAPK/NF-κB and Keap1/Nrf2/HO-1 pathway
Huanwu Hong, Siyue Lou, Fanli Zheng, Hang Gao, Nina Wang, Shasha Tian, Guozheng Huang, Huajun Zhao
Topics & Concepts
Proinflammatory cytokineBronchoalveolar lavageInflammationMAPK/ERK pathwayNF-κBOxidative stressLipopolysaccharidePharmacologyIκBαTumor necrosis factor alphaMedicineChemistryImmunologySignal transductionLungInternal medicineBiochemistryInflammasome and immune disordersInterstitial Lung Diseases and Idiopathic Pulmonary FibrosisImmune Response and Inflammation