Engineering a homochiral metal–organic framework based on an amino acid for enantioselective separation
Haitong Tang, Ke‐Ke Yang, Kunyu Wang, Qi Meng, Fan Wu, Yu Fang, Xiang Wu, Yougui Li, WenCheng Zhang, Yunfei Luo, Chengfeng Zhu, Hong‐Cai Zhou
Abstract
A chiral metal-organic framework possessing an open amphiphilic channel is constructed from a dicarboxylate ligand derived from an amino acid and is shown to be an efficient and recyclable chiral solid adsorbent, which is capable of separating racemic secondary alcohols, epoxides, and ibuprofen with very high enantioselectivity.
Topics & Concepts
Enantioselective synthesisMetal-organic frameworkMetalChemistryAmino acidCombinatorial chemistrySeparation (statistics)Organic chemistryComputer scienceCatalysisBiochemistryAdsorptionMachine learningMetal-Organic Frameworks: Synthesis and ApplicationsCrystallography and molecular interactionsChemical Synthesis and Analysis