A novel hybrid organic–inorganic silsesquioxane and cobalt(<scp>ii</scp>) tetrasulphophthalocyanine material as an efficient electrochemical sensor for the simultaneous determination of the anti-hypertensive nifedipine and its metabolite
João Paulo Winiarski, Marília Reginato de Barros, Giovana S. Wecker, Gláucio R. Nagurniak, Renato L. T. Parreira, Ricardo F. Affeldt, Rosely A. Peralta, Cristiane Luisa Jost
Abstract
A novel electrochemical sensor was applied to determination of anti-hypertensive nifedipine through reduction in the presence of its main metabolite.
Topics & Concepts
NifedipineMetaboliteSilsesquioxaneElectrochemistryMaterials scienceCobaltElectrochemical gas sensorElectrodeCombinatorial chemistryChemistryBiochemistryPolymerMetallurgyPhysical chemistryComposite materialCalciumAnalytical Chemistry and SensorsElectrochemical sensors and biosensorsPorphyrin and Phthalocyanine Chemistry