Facile assembly of three cycloalkyne-modules onto a platform compound bearing thiophene <i>S</i>,<i>S</i>-dioxide moiety and two azido groups
Tomohiro Meguro, Yuki Sakata, Takamoto Morita, Takamitsu Hosoya, Suguru Yoshida
Abstract
An efficient method to assemble three cycloalkyne-modules onto a platform compound bearing a thiophene S,S-dioxide moiety and two azido groups has been developed. The sequential reactions without catalysis or additives enabled the facile preparation of trifunctional molecules by a simple procedure. One-pot assembly was also achieved using the platform and three cycloalkynes.
Topics & Concepts
MoietyThiopheneChemistryCatalysisMoleculeCombinatorial chemistryPolymer chemistryStereochemistryOrganic chemistryClick Chemistry and ApplicationsChemical Synthesis and AnalysisMolecular Junctions and Nanostructures