Mechanical Force for the Transformation of Aziridine into Imine
Sangmin Jung, Hyo Jae Yoon
Abstract
Abstract Force‐selective mechanochemical reactions may be important for applications in polymer mechanochemistry, yet it is difficult to achieve such reactions. This paper reports that cis ‐N‐phthalimidoaziridine incorporated into a macromolecular backbone undergoes migration of N‐phthalimido group to afford imine under mechanochemical condition and not thermal one. The imine is further hydrolyzed by water bifurcating into amine and aldehyde. These structural transformations are confirmed by 1 H NMR and FT‐IR spectroscopic analyses. Computational simulations are conducted for the aziridine mechanophore to propose the mechanism of reaction and define the substrate scope of reaction.
Topics & Concepts
ImineAziridineMechanochemistryAldehydeAmine gas treatingMacromoleculeChemistryReaction mechanismMaterials sciencePolymer chemistryOrganic chemistryCatalysisRing (chemistry)BiochemistryForce Microscopy Techniques and ApplicationsCrystallography and molecular interactionsMechanical and Optical Resonators