α- and β-Santalols Delay Aging in <i>Caenorhabditis elegans</i> via Preventing Oxidative Stress and Protein Aggregation
A. Mohankumar, Kalaiselvi Duraisamy, Govindhan Thiruppathi, Muthusaravanan Sivaramakrishnan, Sundararaj Nivitha, Corey Levenson, Shinkichi Tawata, P. Sundararaj
Abstract
5, which extend longevity and help minimize age-induced protein oxidation and aggregation. We believe that these findings will further promote α- and β-santalol to become next-generation prolongevity and antiaggregation molecules for longer and healthier life.
Topics & Concepts
Caenorhabditis elegansRNA interferenceGeneBiologyProtein aggregationLongevityGene expressionOxidative stressTranscription (linguistics)Genetic screenGeneticsCell biologyRNAPhenotypeBiochemistryLinguisticsPhilosophyBiochemical and biochemical processesGenetics, Aging, and Longevity in Model OrganismsPlant biochemistry and biosynthesis