Small RNAs Activate Salmonella Pathogenicity Island 1 by Modulating mRNA Stability through the <i>hilD</i> mRNA 3′ Untranslated Region
Sabrina Z. Abdulla, Kyungsub Kim, Muhammad S. Azam, Yekaterina A. Golubeva, Fatih Çakar, James M. Slauch, Carin K. Vanderpool
Abstract
Salmonella enterica serovar Typhimurium is a prominent foodborne pathogen, infecting millions of people a year. To express virulence genes at the correct time and place in the host, Salmonella uses a complex regulatory network that senses environmental conditions.
Topics & Concepts
BiologyUntranslated regionRNase PPathogenicity islandSalmonella entericaMessenger RNATranslation (biology)SalmonellaRNACell biologyGeneticsGeneBacteriaSalmonella and Campylobacter epidemiologyRNA and protein synthesis mechanismsBacteriophages and microbial interactions